Insider Ownership

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Name	Relationship / Title	Current Shares	Trading Activity
ahlholm frederick w	Officer	834	View
Date	Type	Shares Traded	Price Range USD
06/22/2007	Statement of Ownership	0	n/a
baldino, jr., ph.d., frank	Director	67,634	View
Date	Type	Shares Traded	Price Range USD
07/01/2008	Acquisition (Non Open Market)	8,804	0.71
04/01/2008	Acquisition (Non Open Market)	14,205	0.44
01/02/2008	Acquisition (Non Open Market)	8,333	0.75
10/01/2007	Acquisition (Non Open Market)	3,956	1.58
07/02/2007	Acquisition (Non Open Market)	2,948	2.12
04/02/2007	Acquisition (Non Open Market)	2,273	2.75
01/03/2007	Acquisition (Non Open Market)	2,490	2.51
10/02/2006	Acquisition (Non Open Market)	1,653	3.78
07/03/2006	Acquisition (Non Open Market)	1,761	3.55
04/03/2006	Acquisition (Non Open Market)	930	6.72
01/03/2006	Acquisition (Non Open Market)	1,032	5.45
10/01/2005	Acquisition (Non Open Market)	1,013	5.55
07/01/2005	Acquisition (Non Open Market)	1,262	4.95
04/01/2005	Acquisition (Non Open Market)	1,157	5.40
bernstein, m.d., ph.d., howard	Officer	52,247	View
Date	Type	Shares Traded	Price Range USD
01/02/2007	Option Execute	5,842	1.26
bohlin garen g	Director	40,565	View
Date	Type	Shares Traded	Price Range USD
07/01/2008	Acquisition (Non Open Market)	10,565	0.71
fenwick, sandra l.	Director	33,020	View
Date	Type	Shares Traded	Price Range USD
07/01/2008	Acquisition (Non Open Market)	10,565	0.71
07/02/2007	Acquisition (Non Open Market)	3,538	2.12
05/03/2007	Acquisition (Non Open Market)	5,000	2.75 - 2.77
05/02/2007	Acquisition (Non Open Market)	5,000	2.68 - 2.70
10/02/2006	Acquisition (Non Open Market)	1,984	3.78
07/03/2006	Acquisition (Non Open Market)	2,347	3.55
04/03/2006	Acquisition (Non Open Market)	1,178	6.72
01/03/2006	Acquisition (Non Open Market)	1,146	5.45
10/01/2005	Acquisition (Non Open Market)	1,126	5.55
07/01/2005	Acquisition (Non Open Market)	1,136	4.95
greenacre martyn d	Director	33,232	View
Date	Type	Shares Traded	Price Range USD
07/01/2008	Acquisition (Non Open Market)	10,565	0.71
05/16/2007	Buy	10,000	2.55 - 2.58
lemke-von ammon, derek	Director	63,109	View
Date	Type	Shares Traded	Price Range USD
07/01/2008	Acquisition (Non Open Market)	10,565	0.71
04/01/2008	Acquisition (Non Open Market)	17,045	0.44
01/02/2008	Acquisition (Non Open Market)	1	10000.00
10/01/2007	Acquisition (Non Open Market)	4,747	1.58
07/02/2007	Acquisition (Non Open Market)	3,538	2.12
04/02/2007	Acquisition (Non Open Market)	2,727	2.75
01/03/2007	Acquisition (Non Open Market)	2,988	2.51
10/02/2006	Acquisition (Non Open Market)	1,984	3.78
07/03/2006	Acquisition (Non Open Market)	1,878	3.55
04/03/2006	Acquisition (Non Open Market)	930	6.72
01/03/2006	Acquisition (Non Open Market)	1,032	5.45
10/01/2005	Acquisition (Non Open Market)	1,013	5.55
07/01/2005	Acquisition (Non Open Market)	1,136	4.95
04/01/2005	Acquisition (Non Open Market)	1,041	5.40
oberg, sherri c.	Officer	141,699	View
Date	Type	Shares Traded	Price Range USD
04/02/2007	Disposition (Non Open Market)	16,000	n/a
04/02/2007	Disposition (Non Open Market)	16,000	n/a
04/02/2007	Acquisition (Non Open Market)	16,000	n/a
04/02/2007	Acquisition (Non Open Market)	16,000	n/a
05/19/2006	Disposition (Non Open Market)	6,600	n/a
05/19/2006	Disposition (Non Open Market)	6,600	n/a
05/19/2006	Acquisition (Non Open Market)	6,600	n/a
05/19/2006	Acquisition (Non Open Market)	6,600	n/a
04/25/2006	Option Execute	2,756	0.84
04/25/2006	Option Execute	2,756	0.84
12/15/2005	Acquisition (Non Open Market)	8,000	n/a
12/15/2005	Acquisition (Non Open Market)	8,000	n/a
12/15/2005	Disposition (Non Open Market)	8,000	n/a
12/15/2005	Disposition (Non Open Market)	8,000	n/a
12/13/2005	Option Execute	1,600	0.84
12/13/2005	Option Execute	1,600	0.84
12/13/2005	Option Execute	1,500	0.84
12/13/2005	Option Execute	1,500	0.84
walovitch, ph.d, richard	Officer	3,000	View
Date	Type	Shares Traded	Price Range USD
12/08/2005	Statement of Ownership	0	n/a

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